The UK national demonstration was held one day before the 74th annual Nakba Day on 15 May, which commemorates the 750,000 Palestinians expelled with the Israeli state's 1948 creation.
It comes as Israeli forces shot dead veteran Palestinian journalist Shireen Abu Akleh, 51, as she covered an Israeli security raid in the occupied West Bank on Wednesday before brutally assaulting mourners at her funeral on Friday.
"Let us tell Shireen that her last report from the occupied territories and her funeral scene – as you all have seen – was the most influential and will continue to be the most visible and the most etched in our memory," Palestinian Forum in Britain (PFB) Chair Zaher Birawi said in a speech.
"You Shireen, your blood was a great curse on the occupation – a great curse on the occupation, its racist and terrorist army and the hypocrisy capitals in the West.
"Yes, dear friends and comrades, it was the most influential report, simply because she wrote it with her precious blood that she gave for the homeland and its capital, Jerusalem.
"Rest in peace Shireen. Rest in peace Shireen as your blood will shorten the way to the liberated Jerusalem and to the liberated Palestine."
Protesters chanted for justice for the celebrated Al Jazeera correspondent and held placards showcasing her photograph.
"She was the voice of Palestine – her voice resonated in our ears in the Second Intifada, when I grew up," said Palestinian university lecturer Dima Srouji, 31, referring to a major uprising against Israel from 2000 to 2005.
"She made us feel heard. I think, at the time, it was worse to be silenced than to die and it still feels that way sometimes.
"Now what's happening is that we are both silenced and dying at the same time. And the problem with Shireen's death is that it incorporates both things," the protester said while holding a banner featuring Palestinian imagery and Abu Akleh's face alongside text that read: "Her voice will forever resonate."
Srouji and others from the master's programme in city design at London's Royal College of Art created the banner to be brought to Saturday's protest.
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